(R,S)-Ivosidenib ((R,S)-AG-120)
国际站：(R,S)-Ivosidenib ((R,S)-AG-120)
CAS：2070009-31-1
纯度：98.49%
分子量：582.96
Formula：C28H22ClF3N6O3
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 2 years |
| -20°C | 1 year |
产品活性：(R,S)-Ivosidenib ((R,S)-AG-120) 是 Ivosidenib (AG-120) 的对映体，活性较低。
生物活性：(R,S)-Ivosidenib ((R,S)-AG-120)是Ivosidenib (AG-120)活性较低的对映体[1]。
参考文献：[1]. Popovici-Muller J, et al. Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1Mutant Cancers. ACS Med Chem Lett. 2018 Jan 19;9(4):300-305.